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Informazioni Personali
Vcalabro
Informazioni Didattiche

2015-2001

 

 Associate Professor of Genetics, University of Naples “Federico II”, Italy

2001-1991

 

Researcher at the Department of Genetics, General and Molecular Biology. University of Naples “Federico II”, Italy

1990-1991

 

Fellow at the RPMS (Royal Postgraduate Medical School of London), UK.

1989-1990

 

Fellow at the National Center for Research (CNR), Cosenza, Italy

1986-1989

 

PhD training in “molecular embryology at the Faculty of Veterinary Medecine, University of Naples “Federico II”.

1984-1985

 

Post-lauream training in the laboratory of Molecular Biology, Department of Genetics, University of Naples “Federico II”

Main activities and responsabilities

 

 

-         Group leader at the Department of Biology University of Naples “Federico II”

-         Head of a C.I.B. Research Unit (Consorzio Inter-Universitario per le Biotecnologie).

-         Member of the GEAR (Competenza Regionale per il Trasferimento Tecnologico Industriale della Genomica Strutturale e Funzionale di Organismi Superiori). 

-        Member of the Teaching Board for the PhD in Biotechnological Sciences, University of Naples, Italy.

-        Member of the A.G.I. (Associazione Genetica Italiana) Steering Committee.

-        Member of the Teaching Committee for the Course of Molecular and Industrial Biotechnology, University of Naples “Federico II”.

-        Reviewer for Project of the “C- "Quinquennial Review of the Cancer Research UK Cell Transformation Research Group".

-        Reviewer MIUR for the "Futuro in ricerca" projects.

-        Invited speaker at 37° Annual Convention of the European Society for Dermatologic Research. Zurich 2007.

-        Chairman e Speaker at National Convention of Italian Association EEC syndrome (Zelarino – Venezia 2010).

-        Chairman and Speaker at Joint Meeting AGI-SIBV-SIGA Assisi 2011.

-        Invited Speaker at  V workshop on p63/p73 Cell death and Differentiation Conferences. IARC, Lione, France, 2011.

-        Invited Speaker at EXPO 2015.

 

-        Recipient of research grants from national institutions (C.I.B., MIUR, Telethon, AIRC and PSR124 HC).

-        Author of 47 publications in Internation Peer Reviewed Journals.

 

Scientific interests

 

Prof. Viola  Calabrò has a long expertise in the field of genome structure and expression as testified by her Academic activity and her scientific interests:

2002-2015  Functional characterization of TP63 gene products in epithelial development and differentiation. Rare genetic diseases (ectodermal dysplasias) Analysis of the molecular mechanism in epithelial cancer pathogenesis.

2000-2002 Role of INK4A and p14ARF in the control of cell proliferation and transformation.

1992-2000 Gene mapping on 3p21 and isolation of zinc-finger genes

1982-1991 Genetic variability in human populations.

Teaching activity

 

              

2015-2001

 

Chair of Genetics for the Bachelor’s Degree in Biotechnological Science

Chair of System Biology for the Master Degree in Biotechnological Science

2005-2015

 

Teacher for the PhD courses in Industrial and molecular Biotechnology

 

  • Maria Vivo, Rosa Fontana, Michela Ranieri, Giuseppina Capasso, Tiziana Angrisano, Alessandra Pollice, Viola Calabrò, Girolama La Mantia. P14ARF interacts with the focal adhesion kinase and protects cells from anoikis. Oncogene 2017. Doi: 10.1038/onc.2017.104

 

  • Cristina Pagano, Orsola di Martino, Nathalie Muller, Andrea Maria Guarino, Rima Siauciunaite, Markus Reischl, Nickolas Simon Foulkes, Daniela Vallone and Viola Calabrò. The tumor-associated YB-1 protein: New player in the circadian control of cell proliferation. Oncotarget. 2017.8(4):6193-6205

 

  • O. Di Martino, Troiano A., Guarino AM, Pollice A, Vivo M., La Mantia G., Calabrò V. DNp63a controls YB-1 protein stability: evidence on YB-1 as a new player in keratinocyte differentiation. Genes Cells 2016 May. Doi:10.111/gtc.12373

 

 

  • Troiano A., Schiano Lo Moriello I, O. di Martino, S. Fusco, A. Pollice, M. Vivo, G. La Mantia, V. Calabrò. Y-Box binding protein-1 is part of a complex molecular network linking DNp63a to the PI3K/AKT pathway in cutaneous squamous cell carcinoma. J. Cell. Physiol. Jan 29. Doi: 10.1002/jcp.24934, 2015.

 

 

  • Vivo M, Matarese M, Sepe M, Di Martino R, Festa L, Calabrò V, La Mantia G, Pollice A. MDM2-mediated degradation of p14ARF: a novel mechanism to control ARF levels in cancer cells. PLoS One Feb 27; 10(2):e0117252. Doi: 10.1371/journal.pone.0117252, 2015.
  • Amoresano A., Di Costanzo A., Leo G., Di Cunto F., La Mantia G., Guerrini L., Calabrò V. Identification of DNp63a protein interactions by Mass Spectometry. Journal of Proteome Research, vol 9 (4). (2010) 2042-2048
  • Vivo M.,  Ranieri M., Sansone F., Santoriello C., Calogero R.A., Calabrò V., Pollice A., La Mantia G. Mimicking p14ARF phosphorylation influences its ability to restrain cell proliferation. PlosOne 8 (1) : e53631. January 2013.
  • Di Costanzo A., Troiano A., Di Martino O., Cacace A., Natale C.F., Ventre M., Netti P., Caserta S., Pollice A., La Mantia G., Calabrò V. The p63 protein isoforms DNp63a modulates Y-box binding protein 1 in its subcellular distribution and regulation of cell survival and motility genes. J. Biol. Chem. (2012) 287(36):30170-80. DOI:10.1074/jbc.M112.34995.
  • Di Costanzo A., Festa L., Roscigno G., Vivo M., Pollice A., Morasso M., La Mantia G. and Calabrò V. A dominant mutation etiologic for human Tricho-Dento-Osseus syndrome impairs the ability of DLX3 to downregulate DNp63a. J. Cell Physiol. (2011) 226 (8) :2189-97.
  • Galli F., Rossi M., D’Alessandra Y., De Simone M., Lopardo T., Haupt Y., Alscheich-Bartok O., Anzi S., Shaulian E., Calabrò V., La Mantia G. and Guerrini L. MDM2 and FBW7 cooperate to induce p63 protein degradation following DNA damage. (2010) J. of Cell Science 123: 2423-33.
Tematiche di Ricerca
1.

Human Molecular Genetics

2.

Cancer genetics

3.

Skin hereditary diseases

Parole Chiave
1.

cancer genetics

2.

oncosuppressor genes

Un pensiero su “Vcalabro

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